Published Works of Dr. Tien-Wen Lee

Scientific Contributions of Dr. Lee

1. Negative relationship between inter-regional interaction and regional power: a resting fMRI study
Preprint Feb 2024
Tien-Wen Lee, Gerald Tramontano
Background Regional neural response and network property used to be treated separately. However, evidence has suggested an intimate relationship between the regional and inter-regional profiles. This research aimed to investigate the influence of functional connectivity on regional spontaneous activity…

2. Concordant dynamic changes of global network properties in the frontoparietal and limbic compartments: An EEG study
Article
Dec 2023
Tien-Wen Lee, Gerald Tramontano, Clay Hinrichs

3. Tripod transcranial alternating current stimulation at 5-Hz to alleviate anxiety symptoms: a preliminary report
Preprint
Oct 2023
Tien-Wen Lee, Chiang-Shan Lee, Gerald Tramontano
Introduction: One of the most common applications of transcranial electrical stimulation (tES) at low current intensity is to induce a relaxed state or reduce anxiety. With technical advancement, different waveforms, montages, and parameters can be incorporated into the treatment regimen.

4. Connectivity changes following transcranial alternating current stimulation at 5-Hz: an EEG study
Preprint
Oct 2023
Tien-Wen Lee, Chiang-shan Ray Li, Gerald Tramontano
Introduction Transcranial alternating current stimulation (tACS) at 5-Hz to the right hemisphere can alleviate anxiety symptoms. This study aimed to explore the connectivity changes following the treatment. Methods We collected electroencephalography (EEG) data from 24 participants with anxiety disorders before and after the tACS treatment during a…

5. Concordant dynamic changes of global network properties in the frontoparietal and limbic compartments: an EEG study
Preprint
Oct 2023
Tien-Wen Lee
Gerald Tramontano
Clay Hinrichs
Introduction Despite its complexity, deciphering nodal interaction is imperative to understanding a neural network. Network interaction is an even more complicated topic that must be addressed. This study aimed to examine the relationship between the brain waves of two canonical brain structures, i.e., the frontoparietal and limbic compartments, du…

6. Regional spectral ratios as potential neural markers to identify mild cognitive impairment related to Alzheimer’s disease
Article
May 2022
Tien-Wen Lee
Gerald Tramontano
Objective Alzheimer’s disease (AD) has prolonged asymptomatic or mild symptomatic periods. Given that there is an increase in treatment options and that early intervention could modify the disease course of AD, it is desirable to devise biological indices that may differentiate AD and nonAD at mild cognitive impairment (MCI) stage. Methods Based o…

7. Automatic parcellation of resting-state cortical dynamics by iterative community detection and similarity measurements
Article
Full-text available
Sep 2021
Tien-Wen Lee
Gerald Tramontano
To investigate the properties of a large-scale brain network, it is a common practice to reduce the dimension of resting state functional magnetic resonance imaging (rs-fMRI) data to tens to hundreds of nodes. This study presents an analytic streamline that incorporates modular analysis and similarity measurements (MOSI) to fulfill functional parce…

Full list at https://www.researchgate.net/scientific-contributions/Tien-Wen-Lee-2194435266

Published Works of Dr. Lee

Academic Papers
1. No association between butyrylcholinesterase K-variant and Alzheimer disease in Chinese. American Journal of Medical Genetics 96: 167-169, 2000.

2. The efficacy and safety of olanzapine for the treatment of geriatric psychosis. Journal of Clinical Psychopharmacology 23:113-118, 2003.

3. Clinical and phenomenological comparisons of delusional and non-delusional major depression in the Chinese elderly. International Journal of Geriatric Psychiatry 18: 479-485, 2003.

4. Severe cardiovascular side effects of olanzapine in an elderly patient. International Journal of Psychiatry in Medicine 33: 399-401, 2003.

5. Effect of age and global function score on schizophrenic P300 characteristics. Neuropsychobiology 51: 45-52, 2004.

6. Subthalamic nucleus stimulation and the development of delusion. Journal of Psychiatric Research 38: 637-638, 2004.

7. Loudness dependence of the auditory evoked potential and antidepressant response in Chinese major depressives. Journal of Psychiatry & Neuroscience 30: 202-205, 2005.

8. Serotonin dysfunction and suicide attempts in major depressives: an auditory event-related potential study. Neuropsychobiology 52: 28-36, 2005.

9. Imitating expressions: Emotion-specific neural substrates in facial mimicry. Social Cognitive Affective Neuroscience 1: 122-135, 2006.

10. Microelectrode recording can be a good adjunct in magnetic resonance image–directed subthalamic nucleus deep brain stimulation for parkinsonism. Surgical Neurology 65: 253-261, 2006.

11. Controlling emotional expression: Behavioural and neural correlates of non-imitative emotional responses. Cerebral Cortex 18: 104-113, 2008.

12. Subcortical Processes of Motor Response Inhibition during a Stop Signal Task. Neuroimage 41: 1352-1363, 2008.

13. Error-specific medial cortical and subcortical activity during the stop signal task: A functional magnetic resonance imaging study. Neuroscience 155: 1142-1151, 2008.

14. Neural Correlates of Speeded as Compared with Delayed Responses in a Stop Signal Task: An Indirect Analog of Risk Taking and Association with an Anxiety Trait. Cerebral Cortex 2008.

15. Cortical and subcortical abnormalities in late-onset depression with history of suicide attempts investigated with MRI and voxel-based morphometry. Journal of Geriatric Psychiatry & Neurology 23: 171-184, 2010.

16. A case of early multiple system atrophy unveiled by antidepressant administration. Acta Neuropsychiatrica 23: 139-140, 2011.

17. Cortical mechanisms of the symptomatology in major depressive disorder: a resting EEG study. Journal of Affective Disorders 131: 243-250, 2011.

18. The effects of Catechol-O-methyl transferase polymorphism Val158Met on functional connectivity in healthy young females: a resting EEG study. Brain Research 1377: 21-31, 2011.

19. The influence of serotonin transporter polymorphism on cortical activity: a resting EEG study. BMC Neuroscience 12:33, 2011.

20. The implication of functional connectivity strength in predicting treatment response of major depressive disorder: a resting EEG study. Psychiatric Research: Neuroimaging 194:372-377, 2011.

21. The influence of NMDA receptor 2B subunit (GRIN2B) on cortical electrical oscillation. World Journal of Neuroscience 1: 38-44, 2011.

22. Do resting brain dynamics predict oddball evoked-potential? BMC Neuroscience 12:121, 2011.

23. A smarter brain is associated with stronger neural interaction: a resting EEG coherence study. Intelligence 40:38-48,2012.

24. The influence of dopamine receptor D4 polymorphism on resting EEG in healthy young females. The Open Journal of Neuroscience 6:19-25, 2012.

25. The influence of Apolipoprotein E epsilon4 and non- epsilon4 polymorphisms on qEEG profiles in healthy young females: a resting EEG study. Brain Topography 25:431-42, 2012.

26. Abnormal neural activity in partially remitted late-onset depression: A preliminary fMRI study of one-back working memory task. Psychiatry Research: Neuroimaging 213:133-41, 2013.

27. Similarity representation of pattern-information fMRI. Chinese Science Bulletin 58: 1236-1242, 2013.

28. Different neural manifestations of two slow frequency bands in resting fMRI: A systemic survey at regional, inter-regional, and network levels. Brain Connectivity 4:242-255, 2014.

29. Resting network is composed of more than one neural pattern: an fMRI study. Neuroscience 274:198-208, 2014.

30. Examination of the validity of the atlas-informed approach to functional parcellation: a resting fMRI study. Neuroreport 28:649-653, 2017.

31. Linking graph features of anatomical architecture to regional brain activity: a multi-modal MRI study. Neuroscience Letters 651:123-127, 2017.

32. Extended cortico-limbic dysregulation model of major depressive disorder: a demonstration of the application of an analysis-synthesis framework to explore psychopathology. International Journal of Psychology Research 11:247-297, 2018.

33. Revisiting functional and structural connectivity of large-scale cortical network. Brain Connectivity 8:129-138, 2018.

34. Limbic and thalamic dynamics may account for default-mode network. European Journal of Neuroscience 47:388-398, 2018.

35. Spontaneous activity in medial orbitofrontal cortex correlates with trait anxiety in healthy male adults. Journal of Zhejiang University-Science B 19:643-653, 2018.

36. Application of analysis-synthesis framework to explore the pathogenic locus of bipolar disorder. International Journal of Psychology Research 12: 121-164, 2018.

37. Does emotion regulation engage the same neural circuit as working memory? A meta-analytical comparison between cognitive reappraisal of negative emotion and 2-back working memory task. PLOS ONE 13:e0203753, 2018.

38. Automatic parcellation of resting-state cortical dynamics by iterative community detection and similarity measurement (submitted, in review).

39. Refinement of neural interaction process: theory of neuro-messenger (review article; in submission).

40. Neural metrics differentiating mild cognitive impairments of AD and nonAD population (in preparation).

Books and Chapters

1. Schizophrenia, suicide and the role of serotonin. In Pompili M et al., ed. Suicide in Schizophrenia. Nova Science Publishers, Inc. 2007.

2. Network Balance and Its Relevance to Affective Disorders: Dialectic Neuroscience. Pronoun 2016 (ISBN 1508044597, 9781508044598; KDP 9781976700200).