Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous system). In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between your brain and the rest of your body. Eventually, the disease can cause the nerves themselves to deteriorate or become permanently damaged.
Signs and symptoms of MS vary widely and depend on the amount of nerve damage and which nerves are affected. Some people with severe MS may lose the ability to walk independently or at all, while others may experience long periods of remission without any new symptoms.
There’s no cure for multiple sclerosis. However, treatments can help speed recovery from attacks, modify the course of the disease and manage symptoms.
Symptoms
Multiple sclerosis signs and symptoms may differ greatly from person to person and over the course of the disease depending on the location of affected nerve fibers. They may include:
- Numbness or weakness in one or more limbs that typically occurs on one side of your body at a time, or the legs and trunk
- Partial or complete loss of vision, usually in one eye at a time, often with pain during eye movement
- Prolonged double vision
- Tingling or pain in parts of your body
- Electric-shock sensations that occur with certain neck movements, especially bending the neck forward (Lhermitte sign)
- Tremor, lack of coordination or unsteady gait
- Slurred speech
- Fatigue
- Dizziness
- Problems with bowel and bladder function
Causes
The cause of multiple sclerosis is unknown. It’s considered an autoimmune disease in which the body’s immune system attacks its own tissues. In the case of MS, this immune system malfunction destroys myelin (the fatty substance that coats and protects nerve fibers in the brain and spinal cord).
Myelin can be compared to the insulation coating on electrical wires. When the protective myelin is damaged and nerve fiber is exposed, the messages that travel along that nerve may be slowed or blocked. The nerve may also become damaged itself.
It isn’t clear why MS develops in some people and not others. A combination of genetics and environmental factors appears to be responsible.
Risk Factors
These factors may increase your risk of developing multiple sclerosis:
- Age. MS can occur at any age, but most commonly affects people between the ages of 15 and 60.
- Sex. Women are about twice as likely as men are to develop MS.
- Family history. If one of your parents or siblings has had MS, you are at higher risk of developing the disease.
- Certain infections. A variety of viruses have been linked to MS, including Epstein-Barr, the virus that causes infectious mononucleosis.
- Race. White people, particularly those of Northern European descent, are at highest risk of developing MS. People of Asian, African or Native American descent have the lowest risk.
- Climate. MS is far more common in countries with temperate climates, including Canada, the northern United States, New Zealand, southeastern Australia and Europe.
- Certain autoimmune diseases. You have a slightly higher risk of developing MS if you have thyroid disease, type 1 diabetes or inflammatory bowel disease.
- Smoking. Smokers who experience an initial event of symptoms that may signal MS are more likely than nonsmokers to develop a second event that confirms relapsing-remitting MS.
Treatment for Acquired and Traumatic Brain Injuries at NCI
An Interdisciplinary Clinical Team Approach
We use a multi-layered treatment approach when treating neurodevelopmental disorders. Patients are treated by an interdisciplinary team of clinicians that includes: a clinical neuropsychologist, a clinical psychologist or behaviorist, a cognitive rehab/speech language therapist and a neuromodulation clinician.
We provide a comprehensive combination of traditional, complementary, as well as, experimental treatments not typically available at any other clinics. For instance, when treating cognitive disorders we typically treat by combining cognitive rehabilitation, with cognitive enhancers, and one or more forms of neuromodulation superimposed on comprehensive behavioral health plan that utilizes specific nutrition requirements, heart-rate variability training, maximizing sleep and the reduction of stress. Similar combination therapies are used for treating a variety of neuropsychiatric conditions such as OCD, as well as, in the treatment of chronic pain and fatigue.
Some of these treatments and consultation options include:
Neurocognitive Rehabilitation
Patients admitted to the cognitive rehabilitation program enter a module based on their primary type of cognitive impairment, e.g., the Attention, Working Memory and Executive System impairment module. Each patient will receive specific treatments for this type of cognitive disorder using a combination of remedial, adaptive and compensatory interventions that have been developed at the NeuroCognitive Institute for their module.
Neuromodulation
We often combine cognitive and language rehabilitation with neuromodulation. Neuromodulation is evolving as a treatment option for treating the cognitive, behavioral and psychiatric symptoms and deficits resulting from neurodevelopmental disorders.
Techniques include invasive procedures such as deep brain stimulation and electroconvulsive therapy (ECT), as well as, non-invasive techniques such as transcranial direct current stimulation tDCS, neurofeedback and rTMS. At NCI, we only use non-invasive neuromodulation intervention combined with other rehabilitation interventions to enhance treatment response.
Speech and Language Therapy
Speech and language therapy focuses on improving speech and abilities to understand and express language.
NCI has speech therapists who can help assess speech delays, restore speech and language skills from young children to adults with neurodevelopmental disorders.
Behavioral Health Interventions
Behavioral health interventions focus on changing or modifying a patient’s lifestyle such as diet and introducing specific exercise programs to enhance cortical and cognitive functioning.
Pharmaceuticals and Nutraceuticals
We use various medications to treat the cognitive, neurobehavioral and neuropsychiatric deficits and symptoms of neurodevelopmental disorders.
Contact Us
If you or know anyone who needs help, contact The NeuroCognitive Institute for assessment and treatment. Call (973) 601 0100 or sign up as a new patient and we will get back to you as soon as we can.
